Product Specifications:
Contents: Epitalon (Epithalon, AEDG peptide)
Size: 10mg
Form: Lyophilized powder
Purity: >99%

Product Overview Mechanism of Action & Biological Studies

Telomerase Activation: Epitalon’s primary research focus is its role as a short-chain peptide thought to interact with DNA. Studies

suggest it can induce the activation of telomerase, an enzyme complex that lengthens telomeres, protective caps at the ends of chromosomes that otherwise shorten with each cell division. Telomerase activation is strongly linked to cellular rejuvenation.Regulation of Gene Expression: Research in models of cellular aging (senescence) investigates Epitalon’s potential to regulate gene expression profiles, shifting them from a senescent state to a more youthful, proliferatively active pattern. Studies explore its effects on cell cycle progression and DNA repair mechanisms.Neuroendocrine & Pineal Gland Modulation: Studies have examined Epitalon’s ability to normalize the production of melatonin by the pineal gland. It is also investigated for its ability to regulate the hypothalamic-pituitary-adrenal (HPA) axis, promoting homeostasis in hormonal cycles that degrade with age.

Research Data and Observed Effects (Preclinical Models)

Cellular Lifespan Studies: In in vitro human fibroblast models, Epitalon has been shown to reactivate dormant telomerase, leading to telomere elongation and significantly extending the cellular lifespan beyond the Hayflick limit.Studies on Biological Aging: Research in various animal models (including mice, rats, and fruit flies) has consistently demonstrated that long-term administration of Epitalon is associated with increased lifespan and reduced markers of biological aging.Immune Function Models: Research investigations have observed Epitalon’s potential to modulate immune system markers, particularly its role in supporting T-cell activity and reversing immune system involution (shrinking) associated with aging.Tumorigenesis

Models: Preclinical studies have evaluated Epitalon’s impact on spontaneous and induced tumor formation, with some research indicating it may help maintain DNA integrity and inhibit carcinogenesis in laboratory models.

Safety, Adverse Effects, and Research Status

Adverse Effects Profile: As a natural peptide analogue, Epitalon generally shows high tolerability in laboratory studies. Most reported findings in peer-reviewed scientific literature indicate no significant acute or chronic toxicity, though research specifically on humans is limited and long-term data is sparse.Regulatory & Research Status: Epitalon remains an investigational agent in pre-clinical and basic research. It has not been approved by any regulatory bodies (such as the FDA, EMA, or MHRA) for human clinical use, diagnostic

purposes, or therapeutic applications outside of authorized scientific research.

This product is provided strictly for laboratory research and analytical testing by qualified scientific professionals. It is not approved for human or veterinary administration, diagnostic protocols, or therapeutic applications.