Product Specifications:Contents: Ipamorelin
Size: 10mg
Form: Lyophilized powder

Purity: >99%

Product Overview
Ipamorelin is a synthetic pentapeptide and selective growth hormone secretagogue (GHS) that acts as an agonist at the growth hormone secretagogue receptor (GHS-R1a / ghrelin receptor). It is utilized in laboratory models to investigate selective anterior pituitary signaling, pulsatile growth hormone (GH) release, and somatotrope regulation.

Active Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
Quantity: 10 mg
Physical Form: Lyophilized powder
Purity Standard: Greater than 99% (HPLC / Mass Spectrometry verified)
Research Domain: Endocrinology, somatotrope receptor selectivity, and GH/IGF-1 axis dynamics

Mechanistic Profile in Research

Selective GHS-R1a Agonism: Ipamorelin selectively binds to the ghrelin receptor on somatotropes in the anterior pituitary gland, stimulating GH release without significantly activating other endocrine cascades.
Minimal Endocrine Crosstalk: Unlike earlier growth hormone-releasing peptides (such as GHRP-2 or GHRP-6), research indicates Ipamorelin does not induce significant elevations in cortisol, adrenocorticotropic hormone (ACTH), prolactin, or aldosterone.
Preservation of Pulsatility: In vivo models show that Ipamorelin promotes GH spikes that closely mimic physiological pulse patterns, preventing constant, non-pulsatile receptor desensitization.
GHRH Synergy: Studies demonstrate enhanced GH output when Ipamorelin is co-administered

in vitro or in vivo with GHRH analogues (such as CJC-1295 / Modified GRF 1-29), illustrating dual-receptor pathway synergy.

Handling and Storage Protocol

Reconstitution: Dilute using sterile Bacteriostatic Water (0.9% Benzyl Alcohol). Direct the diluent slowly down the glass wall of the vial and gently swirl until fully dissolved. Avoid rapid agitation.
Lyophilized Form: Store at -20 degrees C for long-term preservation; shield from direct light exposure.
Reconstituted State: Store refrigerated at 2 degrees C to 8 degrees C and utilize within 28 days to maintain compound stability. Avoid repeated freeze-thaw cycles.

This product is provided strictly for laboratory research and analytical testing by qualified

scientific professionals. It is not approved for human or veterinary administration, diagnostic protocols, or therapeutic applications.