The Shred Stack contains:

Retatrutide – 20MG
Mots-C – 20MG

Product Overview
The Shred Stack is a research-focused combination pairing Retatrutide (LY3437943), a synthetic triple-hormone receptor agonist, with MOTS-c, a mitochondrial-derived peptide (MDP).

This blend is designed to facilitate laboratory investigation into complex metabolic pathways, cellular energy dynamics, and mitochondrial function.
ParameterSpecificationComponentsRetatrutide / MOTS-cQuantity20 mg (Retatrutide) / 40 mg (MOTS-c)FormLyophilized powderPurity

(HPLC verified)Primary ApplicationLaboratory research in metabolic homeostasis & mitochondrial signal transduction
Mechanistic Synergy in Research

Triple Incretin & Glucagon Signaling: Retatrutide targets GLP-1, GIP, and Glucagon (GCGR) receptors. In research models, this pathway regulates satiety, enhances glucose-dependent insulin release, and increases basal metabolic rate through liver fat mobilization.
Mitochondrial & AMPK Regulation: MOTS-c (Mitochondrial Open Reading Frame of the 12S

rRNA Type-c) acts as a metabolic signal, activating the AMPK pathway. It influences cellular energy balance, glucose uptake in skeletal muscle, and insulin sensitivity independently of nuclear DNA pathways.
Combined Metabolic Focus: Studying these two agents together allows researchers to observe potential cross-talk between systemic hormonal signaling (gastrointestinal and pancreatic axes) and cell-autonomous mitochondrial energetics.

Handling & Storage Protocol

Reconstitution: Reconstitute using sterile Bacteriostatic Water (

Benzyl Alcohol). Allow the diluent to flow slowly down the inside wall of the vial and gently swirl until dissolved. Do not shake vigorously.
Lyophilized Powder: Store at

or lower for

long-term stability.
Reconstituted Solution: Refrigerate at

and utilize within 28 days to maintain compound integrity.

This product is provided strictly for laboratory research and analytical testing by qualified researchers. It is not intended for human or veterinary use, therapeutic administration, or commercial distribution.