Product Specifications:
Contents: TB500 (Thymosin B4 Acetate)
Size: 10 mg
Form: Lyophilized powder
Purity: >99%

Product Overview
TB-500 is a synthetic, truncated peptide sequence based on the active domain of naturally occurring Thymosin Beta-4 (T-beta-4). It

is primarily utilized in laboratory settings to investigate actin cytoskeleton organization, angiogenesis, endothelial cell migration, and tissue repair dynamics.

Active Sequence: Thymosin Beta-4 Acetate (typically LKKTETQ fragment)

Quantity: 10 mg

Physical Form: Lyophilized powder

Purity Standard: Greater than 99% (HPLC / Mass Spectrometry verified)

Research Domain: Cell migration, tissue regeneration, and wound healing pathways

Mechanistic Profile in Research

Actin Sequestration: TB-500 acts as an actin-binding protein, sequestering G-actin monomers to maintain the dynamic equilibrium required for cell motility, structure, and matrix repair.

Angiogenesis and Cell Migration: Studies observe that T-beta-4 derivatives upregulate endothelial cell differentiation and promote microvascular network formation in damaged tissues.

Inflammatory Response Modulation: Research models demonstrate its capacity to lower pro-inflammatory cytokines while supporting cell survival in ischemic or wounded tissue environments.

Handling and Storage Protocol

Reconstitution: Dilute using sterile Bacteriostatic Water (0.9% Benzyl Alcohol) or standard sterile saline (0.9% NaCl). Direct the solvent toward the glass wall to prevent foaming.

Lyophilized Form: Store at -20 degrees C for long-term preservation; protect from ambient light.

Reconstituted State: Keep refrigerated at 2 degrees C to 8 degrees C and utilize within 28 days. Avoid repeated freeze-thaw cycles.

This product is intended strictly for laboratory research by qualified scientific professionals. It is not approved for human or veterinary administration, diagnostic protocols, or

therapeutic applications.